New insights into the immunology and evolution of HIV

Fewer than one million HIV infected individuals are currently receiving anti-retroviral therapy. Thelimitations of such treatment have underscored the need to develop more effective strategies to control thespread and pathogenesis of HIV. Typically, naturally occurring protective immune responses provide theparadigm for such development. It is now clear however that HIV can utilise the millieu of an activatedimmune system to its own replicative advantage. Mobilisation of the immune response, intended to thwartof HIV contributes to lack of immune control and the development of progressive disease in the majority ofinfected, untreated individuals. Further delineation of the intimate interactions between the HIV and theimmune system will be critical and recent advances in this direction are discussed.

作 者： JUSTIN STEBBING STEVE PATTERSON FRANCES GOTCH   作者單位： Department of Immunology, Division of Investigative Science, Faculty of Medicine, Imperial College of Science, Technology and Medicine, The Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9NH, United Kingdom  刊 名： 細(xì)胞研究(英文版)  ISTIC SCI 英文刊名： CELL RESEARCH  年，卷(期)： 2003 13(1)  分類號(hào)： Q2  關(guān)鍵詞： HIV   immune response   CTL   evolution   vaccine  

【New insights into the immunology and】相關(guān)文章：

The Trip to New Zealand04-27

初中英語作文：A New Jacket,A New Jacket范文08-09

This is all new to me.05-04

The influence of volcanism on paleoclimate in the northeast of China: Insights from Jinchuan peat, Jilin Province, China04-27

優(yōu)秀教案 The new words of the magician04-25

New Asymmetric Synthesis of Alkannin and Shikonin04-28

Bilateralism: New Thrust of Free Trade04-26

New Sesquiterpenes from Cacalia ainsliaeflora04-27

The New Term新學(xué)期05-20

New Olympic products hit stores05-04